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Manuscripts for 2021

Members of the Burn and Surgical Research Laboratory Published the following papers in 2021:

In-depth examination of hyperproliferative healing in two breeds of Sus scrofa domesticus commonly used for research.Funkhouser CH, Kirkpatrick LD, Smith RD, Moffatt LT, Shupp JW, Carney BC.Animal Model Exp Med. 2021 Nov 22;4(4):406-417. doi: 10.1002/ame2.12188. eCollection 2021 Dec.PMID: 34977492 Free PMC article. Peritraumatic 17β-estradiol levels influence chronic posttraumatic pain outcomes.Linnstaedt SD, Mauck MC, Son EY, Tungate AS, Pan Y, Rueckeis C, Yu S, Lechner M, Datner E, Cairns BA, Danza T, Velilla MA, Pearson C, Shupp JW, Smith DJ, McLean SA.Pain. 2021 Dec 1;162(12):2909-2916. doi: 10.1097/j.pain.0000000000002282.PMID: 34028234 Free PMC article. Use of 816 Consecutive Burn Wound Biopsies to Inform a Histologic Algorithm for Burn Depth Categorization.Phelan HA, Holmes Iv JH, Hickerson WL, Cockerell CJ, Shupp JW, Carter JE.J Burn Care Res. 2021 Nov 24;42(6):1162-1167. doi: 10.1093/jbcr/irab158.PMID: 34387313 Peritraumatic Vitamin D Levels Predict Chronic Pain Severity and Contribute to Racial Differences in Pain Outcomes Following Major Thermal Burn Injury.Mauck MC, Barton CE, Tungate A, Shupp JW, Karlnoski R, Smith DJ, Williams FN, Jones SW, McGrath KV, Cairns BA, McLean SA.J Burn Care Res. 2021 Nov 24;42(6):1186-1191. doi: 10.1093/jbcr/irab031.PMID: 33564878 Free PMC article. A Pilot Study of Negative Pressure Therapy with Autologous Skin Cell Suspensions in a Porcine Model.Carney BC, Moffatt LT, Travis TE, Nisar S, Keyloun JW, Prindeze NJ, Oliver MA, Kirkpatrick LD, Shupp JW.J Surg Res. 2021 Nov;267:182-196. doi: 10.1016/j.jss.2021.05.010. Epub 2021 Jun 18.PMID: 34153561 Free article. Examining the effect of wound cleansing on the microbiome of venous stasis ulcers.Ernlund AW, Moffatt LT, Timm CM, Zudock KK, Howser CW, Blount KM, Alkhalil A, Shupp JW, Karig DK.Wound Repair Regen. 2021 Sep;29(5):766-776. doi: 10.1111/wrr.12926. Epub 2021 May 15.PMID: 33991156 Representation Matters: An Assessment of Diversity in Current Major Textbooks on Burn Care.Shivega WG, McLawhorn MM, Tejiram S, Travis TE, Shupp JW, Johnson LS.J Burn Care Res. 2021 Aug 4;42(4):617-620. doi: 10.1093/jbcr/irab066.PMID: 33928373 Initial Experience Combining Negative Pressure Wound Therapy With Autologous Skin Cell Suspension and Meshed Autografts.Carney BC, Johnson LS, Shupp JW, Travis TE.J Burn Care Res. 2021 Aug 4;42(4):633-641. doi: 10.1093/jbcr/irab075.PMID: 33903907 Free PMC article. Utility of 30-Day Readmission Metrics in the Burn Population: Navigating Quality Metric Limitations in Special Populations.Prindeze NJ, Shupp JW, Johnson LS.J Burn Care Res. 2021 Aug 4;42(4):711-715. doi: 10.1093/jbcr/iraa203.PMID: 33591321 Cutaneous Thermal Injury Modulates Blood and Skin Metabolomes Differently in a Murine Model.Alkhalil A, Ball RL, Garg G, Day A, Carney BC, Kumar R, Hammamieh R, Moffatt LT, Shupp JW.J Burn Care Res. 2021 Aug 4;42(4):727-742. doi: 10.1093/jbcr/iraa209.PMID: 33301570 Free PMC article. A phase 3, open-label, controlled, randomized, multicenter trial evaluating the efficacy and safety of StrataGraft® construct in patients with deep partial-thickness thermal burns.Gibson ALF, Holmes JH 4th, Shupp JW, Smith D, Joe V, Carson J, Litt J, Kahn S, Short T, Cancio L, Rizzo J, Carter JE, Foster K, Lokuta MA, Comer AR, Smiell JM, Allen-Hoffmann BL.Burns. 2021 Aug;47(5):1024-1037. doi: 10.1016/j.burns.2021.04.021. Epub 2021 Apr 23.PMID: 34099322 Free article. Clinical Trial.

Circulating Syndecan-1 and Tissue Factor Pathway Inhibitor, Biomarkers of Endothelial Dysfunction, Predict Mortality in Burn Patients.Keyloun JW, Le TD, Pusateri AE, Ball RL, Carney BC, Orfeo T, Brummel-Ziedins KE, Bravo MC, McLawhorn MM, Moffatt LT, Shupp JW; and the SYSCOT study group.Shock. 2021 Aug 1;56(2):237-244. doi: 10.1097/SHK.0000000000001709.PMID: 33394974 Free PMC article. Institutional Experience Using a Treatment Algorithm for Electrical Injury.Nisar S, Keyloun JW, Kolachana S, McLawhorn MM, Moffatt LT, Travis TE, Shupp JW, Johnson LS.J Burn Care Res. 2021 May 7;42(3):351-356. doi: 10.1093/jbcr/irab020.PMID: 33530107 Cross-Sectional Assessment of Burn Center and Nonburn Center Patient Care: A Multi-Database Comparison.Prindeze NJ, Marano MA, Shupp JW, Johnson LS.J Burn Care Res. 2021 May 7;42(3):376-380. doi: 10.1093/jbcr/iraa006.PMID: 33079173 Pediatric Treadmill Friction Burns to the Hand: Outcomes of an Initial Nonoperative Approach.Batra N, Zheng Y, Alberto EC, Ahmed OZ, Cheng M, Shupp JW, Burd RS.J Burn Care Res. 2021 May 7;42(3):434-438. doi: 10.1093/jbcr/iraa178.PMID: 33022715 Porcine Xenograft and Epidermal Fully Synthetic Skin Substitutes in the Treatment of Partial-Thickness Burns: A Literature Review.Haller HL, Blome-Eberwein SE, Branski LK, Carson JS, Crombie RE, Hickerson WL, Kamolz LP, King BT, Nischwitz SP, Popp D, Shupp JW, Wolf SE.Medicina (Kaunas). 2021 Apr 30;57(5):432. doi: 10.3390/medicina57050432.PMID: 33946298 Free PMC article. Review. Modeling Burn Progression Using Comb Burns: The Impact of Thermal Contact Duration on Model Outcomes.Smith RD Jr, Carney BC, Garg G, Monger KW, Prindeze NJ, Shupp JW, Moffatt LT.J Surg Res. 2021 Apr;260:155-162. doi: 10.1016/j.jss.2020.11.068. Epub 2020 Dec 16.PMID: 33340869 Hypopigmented burn hypertrophic scar contains melanocytes that can be signaled to re-pigment by synthetic alpha-melanocyte stimulating hormone in vitro.Carney BC, Travis TE, Moffatt LT, Johnson LS, McLawhorn MM, Simbulan-Rosenthal CM, Rosenthal DS, Shupp JW.PLoS One. 2021 Mar 25;16(3):e0248985. doi: 10.1371/journal.pone.0248985. eCollection 2021.PMID: 33765043 Free PMC article. Early abnormal fibrinolysis and mortality in patients with thermal injury: a prospective cohort study.Pusateri AE, Le TD, Keyloun JW, Moffatt LT, Orfeo T, Brummel-Ziedins KE, McLawhorn MM, Callcut RA, Shupp JW; SYSCOT Study Group.BJS Open. 2021 Mar 5;5(2):zrab017. doi: 10.1093/bjsopen/zrab017.PMID: 33893737 Free PMC article. An Assessment of Research Priorities to Dampen the Pendulum Swing of Burn Resuscitation.Burmeister DM, Smith SL, Muthumalaiappan K, Hill DM, Moffatt LT, Carlson DL, Kubasiak JC, Chung KK, Wade CE, Cancio LC, Shupp JW.J Burn Care Res. 2021 Mar 4;42(2):113-125. doi: 10.1093/jbcr/iraa214.PMID: 33306095 Coming to Consensus: What Defines Deep Partial Thickness Burn Injuries in Porcine Models?Gibson ALF, Carney BC, Cuttle L, Andrews CJ, Kowalczewski CJ, Liu A, Powell HM, Stone R, Supp DM, Singer AJ, Shupp JW, Stalter L, Moffatt LT.J Burn Care Res. 2021 Feb 3;42(1):98-109. doi: 10.1093/jbcr/iraa132.PMID: 32835360 Free PMC article. Why Are Infections Important in Burn Patients?Jeschke MG, Chung KK, Shupp JW.Surg Infect (Larchmt). 2021 Feb;22(1):1-2. doi: 10.1089/sur.2020.305. Epub 2020 Sep 1.PMID: 32881644 No abstract available. Bacterial Virulence Factors and Their Contribution to Pathophysiology after Thermal Injury.Nisar S, Kirkpatrick LD, Shupp JW.Surg Infect (Larchmt). 2021 Feb;22(1):69-76. doi: 10.1089/sur.2020.188. Epub 2020 Jul 28.PMID: 32735479 Innovations in Infection Prevention and Treatment.Tejiram S, Shupp JW.Surg Infect (Larchmt). 2021 Feb;22(1):12-19. doi: 10.1089/sur.2020.202. Epub 2020 Jul 22.PMID: 32716696 Review. Hypochlorous Acid Solution Is Safe for Intracavitary Lavage: Examination in a Rodent Model.Ball RL, Garg G, Vazquez JS, Day A, Moffatt LT, Robson MC, Shupp JW.Eplasty. 2021 Jan 9;21:e1. eCollection 2021.PMID: 33488909 Free PMC article. Review of the Terminology Describing Ionizing Radiation-Induced Skin Injury: A Case for Standardization.Burnett LR, Hughes RT, Rejeski AF, Moffatt LT, Shupp JW, Christy RJ, Winkfield KM.Technol Cancer Res Treat. 2021 Jan-Dec;20:15330338211039681. doi: 10.1177/15330338211039681.PMID: 34613833 Free PMC article. Review. Galectin-1 production is elevated in hypertrophic scar.Kirkpatrick LD, Shupp JW, Smith RD, Alkhalil A, Moffatt LT, Carney BC.Wound Repair Regen. 2021 Jan;29(1):117-128. doi: 10.1111/wrr.12869. Epub 2020 Oct 26.PMID: 33073427


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